Tarner, Ingo H. and Haerle, Peter and Mueller-Ladner, Ulf and Gay, Renate E. and Gay, Steffen (2005) The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 19 (1). pp. 19-35. ISSN 1521-6942, 1521-1770
Full text not available from this repository. (Request a copy)Abstract
Rheumatoid arthritis is a systemic inflammatory disease that, by definition, can affect all parts of the human body, including severe complications such as uveitis/episcleritis and vasculitis of the heart, lungs, kidneys and the central and peripheral nervous systems. Its primary and by far the most common manifestations, however, affect the joints and are characterised by inflammatory reactions and activation of the synovial lining tissue and associated structures, the latter resulting in tenovaginitis and rheumatoid nodules. As all pathophysiological mechanisms are based on pathways that are inherent in the different components of a joint, it is necessary to examine the unique features of normal synovium prior to analysing disease-specific pathways. This chapter will therefore describe the physiological structure of the synovium and the inflammatory pathology of rheumatoid synovitis in early and chronic stages of the disease.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RHEUMATOID-ARTHRITIS SYNOVIUM; FIBROBLAST-LIKE SYNOVIOCYTES; CARTILAGE-PANNUS JUNCTION; ANTIKERATIN ANTIBODIES; VASCULAR MORPHOLOGY; TISSUE MACROPHAGES; GENE-EXPRESSION; CELL INFILTRATE; POSITIVE CELLS; LINING LAYER; synovium; synovitis; rheumatoid arthritis; early RA; fibroblasts; macrophages; T cells; B cells; lymphoid neogenesis; cartilage; adhesion molecules; cytokines; metalloproteinases; neuro-endocrine immunology |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 May 2021 10:34 |
| Last Modified: | 28 May 2021 10:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36501 |
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