Schmidt, U. and Dahlke, M. H. and Klempnauer, J. and Schlitt, Hans Juergen and Piso, Pompiliu (2005) Perioperative morbidity and quality of life in long-term survivors following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. EJSO, 31 (1). pp. 53-58. ISSN 0748-7983, 1532-2157
Full text not available from this repository. (Request a copy)Abstract
Background. Improved prognosis can be achieved in selected patients with peritoneal. carcinomatosis (PC) by major surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). Method. Sixty seven patients with PC were operated with the aim of complete macroscopical. cytoreduction followed by HIPEC (using cisplatin.. mitomycin or mitoxantrone). Quality of life was assessed with the EORTC QLQ-C30 questionnaire. Results. The patients had a variety of primary tumours, including appendix carcinomas (22/67). Mean operating time was 7 hours and complete cytoreduction was achieved in 58% of the patients. Overall morbidity was 34%. Post-operative mortality was 4.5%. The mean score for global health status of long-term survivors (20 questionnaires/25 patients) was 62.6 (73.3 for the control population, p = 0.07). Functional status, particularly the role (56.4) and the social functioning (53.9) were impaired. Conclusion. Cytoreductive surgery combined with HIPEC is associated with an increased morbidity and mortality. Complications are predominantly related to major surgery. Following this aggressive treatment, survivors may achieve a satisfactory quality of life. (C) 2004 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PERITONEAL CARCINOMATOSIS; COLORECTAL-CANCER; RANDOMIZED-TRIAL; MORTALITY; COLON; cytoreductive surgery; morbidity; mortality |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 May 2021 11:54 |
| Last Modified: | 28 May 2021 11:54 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36512 |
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