Expert recommendations: Hepatitis C and transplantation

Zimmermann, T. and Beckebaum, S. and Berg, C. and Berg, T. and Braun, F. and Eurich, D. and Herzer, K. and Neumann, U. and Rupp, C. and Sterneck, M. and Strassburg, C. and Welker, M. -W. and Zachoval, R. and Gotthardt, D. N. and Weigand, K. and Schmidt, H. and Wedemeyer, H. and Galle, P. R. and Zeuzem, S. and Sarrazin, C. (2016) Expert recommendations: Hepatitis C and transplantation. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 54 (7). pp. 665-684. ISSN 0044-2771, 1439-7803

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Abstract

With the approval of new direct acting antiviral agents (DAA), therapeutic options for patients with chronic hepatitis C virus (HCV) infection are now generally available before and after liver transplantation (LT). Interferon-free DAA regimens are highly effective therapies and provide a good safety profile. However, the body of clinical evidence in this patient population is limited and the best treatment strategies for patients on the waiting list with (de) compensated cirrhosis and after LT are not well defined. The following recommendations for antiviral therapy in the context of LT are based on the currently available literature and clinical experience of experts in the field, and have been discussed in an expert meeting. The aim of this article is to guide clinicians in the decision making when treating patients before and after LT with DAAs.

Item Type: Article
Uncontrolled Keywords: STAGE RENAL-DISEASE; VIRUS GENOTYPE 1; SUSTAINED VIROLOGICAL RESPONSE; SOFOSBUVIR PLUS RIBAVIRIN; ORTHOTOPIC LIVER-TRANSPLANTATION; TREATMENT-EXPERIENCED PATIENTS; HUMAN-IMMUNODEFICIENCY-VIRUS; INTERFERON-BASED THERAPY; TREATMENT-NAIVE PATIENTS; CHRONIC KIDNEY-DISEASE; hepatitis C; transplantation; DAA; waiting list; immunosuppression
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Dr. Gernot Deinzer
Date Deposited: 03 Apr 2019 05:11
Last Modified: 03 Apr 2019 05:11
URI: https://pred.uni-regensburg.de/id/eprint/3657

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