Ruhl, Stefan and Rayment, S. A. and Schmalz, Gottfried and Hiller, Karl-Anton and Troxler, R. F. (2005) Proteins in whole saliva during the first year of infancy. JOURNAL OF DENTAL RESEARCH, 84 (1). pp. 29-34. ISSN 0022-0345,
Full text not available from this repository. (Request a copy)Abstract
During the first year of an infant's life, the oral environment is subject to drastic changes that coincide with the eruption of teeth. Proteins in saliva are important for protecting oral surfaces and provide receptors for bacterial adhesins. The objective of this longitudinal study was to monitor the general composition and expression of proteins in whole saliva of infants, to prove the hypothesis that expression of certain proteins changes during infant development, and might be associated with tooth eruption. The results showed a remarkable constancy in the overall pattern of salivary proteins and glycoproteins during infancy. Exceptions were the mucins and albumin. The mucins are expressed differentially, with first MUC7 and later MUC5B being predominant. Albumin, a marker of serum leakage, started to rise in whole saliva preceding tooth eruption. Thus, the expression of only few proteins appears to be changed during infant development.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ACTINOMYCES-NAESLUNDII; ORAL ACTINOMYCES; IMMUNOGLOBULIN-A; MUCINS MG1; CHILDREN; COLONIZATION; STREPTOCOCCI; RECEPTORS; ADHESINS; BACTERIA; saliva; proteins; mucins; infants; development |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Jun 2021 10:55 |
| Last Modified: | 07 Jun 2021 10:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36730 |
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