Neovascularization in prefabricated flaps using a tissue expander and an implanted arteriovenous pedicle

Hoang, Nguyen The and Kloeppel, M. and Staudenmaier, Rainer and Schweinbeck, S. and Biemer, E. (2005) Neovascularization in prefabricated flaps using a tissue expander and an implanted arteriovenous pedicle. MICROSURGERY, 25 (3). pp. 213-219. ISSN 0738-1085,

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Abstract

Creating prefabricated flaps using tissue expanders in combination with the implantation of maximal blood flow vascular pedicles into suitable tissue areas represents a new tendency in the reconstruction of large skin defects. In 42 Chinchilla Bastard female rabbits weighing 3,700-4,600 g, skeletonized arteriovenous pedicles with maximal blood flow, dissected from the femoral and saphena magna bundles, were implanted underneath abdominal fasciocutaneous flaps. Oval tissue expanders of 250 ml were placed and fixed on the abdominal wall to expand these prefabricated flaps. The evaluation parameters were macroscopic observation, blood analysis, selective microangiography, histology, and scintigraphy. The study results showed that neovascularization in expanded prefabricated flaps was established from newly formed vessels generated from the implanted peclicles and their vascular connections with the originally available vasculature in the flap. After 20 days of prefabrication, the entirety of the expanded prefabricated flaps was perfused by blood flow supplied from newly implanted arteriovenous peclicles. The study indicated that an expanded prefabricated flap can be successfully created by the simultaneous implantation of a maximal blood flow pedicle in combination with flap expansion. (c) 2005 Wiley-Liss, Inc.

Item Type: Article
Uncontrolled Keywords: SKIN FLAPS; PLASTIC-SURGERY; EXPANSION; RECONSTRUCTION; COMPLICATIONS; EXPERIENCE; RABBITS; NECK; HEAD;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Jun 2021 10:27
Last Modified: 08 Jun 2021 10:27
URI: https://pred.uni-regensburg.de/id/eprint/36768

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