Proposed new method for angiographically quantifying neovascularization in prefabricated flaps

Hoang, Nguyen The and Kloeppel, M. and Werner, J and Staudenmaier, Rainer and Biemer, E. (2005) Proposed new method for angiographically quantifying neovascularization in prefabricated flaps. MICROSURGERY, 25 (3). pp. 220-226. ISSN 0738-1085,

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Abstract

Prefabricated flaps have many potential applications in plastic and reconstructive surgery. Despite numerous experimental investigations and clinical applications, a standard quantification procedure for analyzing neovascularization in prefabricated flaps has not yet been established in the literature. In this study, we developed a new method for quantifying neovascularization, using a standard integral line plate including 25 evenly spaced lines corresponding to a 15-cm flap length, which was subsequently analyzed under a 2x magnification loupe. Vessel quantity was determined by counting the total number of times that vessels perfused by Micropaque intersected the integral lines over the entire surface of the flap. This new method was used for quantifying neovascularization in 156 prefabricated flaps, and we concluded that this technique is very simple and useful, allowing precise determination of the amount of neovascularization in prefabricated flaps on angiograms. Based on this principle, the quantification of neovascularization in any size of prefabricated flap can be easily performed using suitably modified integral line plates corresponding to the various flap dimensions. (c) 2005 Wiley-Liss, Inc.

Item Type: Article
Uncontrolled Keywords: SKIN FLAPS; RABBITS; EXPERIENCE;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Jun 2021 10:30
Last Modified: 08 Jun 2021 10:30
URI: https://pred.uni-regensburg.de/id/eprint/36769

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