Closing microvascular lesions with fibrin sealant-attached muscle pads

Fehm, Nando P. and Vatankhah, Bijan and Dittmar, Michael S. and Tevetoglu, Yesim and Retzl, Gerald and Horn, Markus (2005) Closing microvascular lesions with fibrin sealant-attached muscle pads. MICROSURGERY, 25 (7). pp. 570-574. ISSN 0738-1085, 1098-2752

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Abstract

Fibrin sealants are used in a variety of surgical procedures, mainly for purposes of hemostasis and assisted wound healing. The combined use of fibrin sealant and autologous muscle pads for hemostasis was not reported previously. Arterial incisions in the common carotid artery in rats were closed by the combined application of fibrin sealant and an autologous muscle pad. Postsurgical vessel patency and degree of stenosis were evaluated by color duplex sonography, computed tomography angiography, and postmortem histology. The combined application of muscle pad and fibrin sealant and achievement of hemostasis was feasible in all animals. Seventy-eight percent of animals showed no or only slight postsurgical vessel stenosis. Our method is simple and quick to perform, showing a high potential for hemostasis in microvascular lesions. Therefore, it might be used in future experimental studies for conservation of vessel patency after arterial catheterization and in experimental or clinical vascular surgery. (c) 2005 Wiley-Liss, Inc.

Item Type: Article
Uncontrolled Keywords: ;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Neurologie
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Jun 2021 10:32
Last Modified: 08 Jun 2021 10:32
URI: https://pred.uni-regensburg.de/id/eprint/36770

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