Baumgart, U. and Schmid, R. and Spiessl, Hermann (2005) Olanzapine-induced acute rhabdomyolysis - A case report. PHARMACOPSYCHIATRY, 38 (1). pp. 36-37. ISSN 0176-3679
Full text not available from this repository. (Request a copy)Abstract
A 29-year-old white man with first diagnosis of acute paranoid schizophrenia received for the first time a neuroleptic medication. On admission, creatine phosphokinase (CK) was within normal range (86 U/l). Two days after initiation of treatment with olanzapine (10 mg per day), the patient complaint about mild muscle jerks, and elevated serum CK (949 U/l) was found. One day later, serum CK raised within hours from 9250 U/l up to 34 503 U/l peak concentration. There was no clinical evidence of a neuroleptic malignant syndrome (NMS) or other muscle diseases. After stopping drug treatment and forced diuresis serum CK returned to normal levels within two weeks without acute renal failure. The case report points to necessity of monitoring serum CK during olanzapine treatment when mild muscular symptoms occur.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEUROLEPTIC MALIGNANT SYNDROME; THERAPY |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Aug 2023 08:54 |
| Last Modified: | 16 Aug 2023 08:54 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36798 |
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