Diffusion-weighted imaging in the diagnostic evaluation of the hydrocephalus in patients with acute or chronic increase in cerebral pressure

Dorenbeck, Ulrich and Schlaier, J. and Feuerbach, S. and Seitz, J. (2005) Diffusion-weighted imaging in the diagnostic evaluation of the hydrocephalus in patients with acute or chronic increase in cerebral pressure. ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 177 (1). pp. 99-104. ISSN 1438-9029,

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Abstract

Purpose: To investigate whether diffusion-weighted imaging (DWI) in magnetic resonance imaging (MRI) provides additional information about the periventricular white matter for the assessment of hydrocephalus. Materials and Methods: Sixteen MRI examinations (11 with acutely increased cerebral pressure, 5 without symptoms) on 15 patients with hydrocephalus (4 patients with communicating hydrocephalus and I I patients with obstructive hydrocephalus) were analyzed. One symptomatic patient subsequently became asymptomatic. We investigated the "apparent diffusion coefficient" (ADC) in the subcortical and periventricular white matter. The ADCs of the study patients were compared with those of a healthy control group. Results: Symptomatic patients with hydrocephalus, 6/11 showed peri-ventricular edema and a significantly higher ADC values in the periventricular region than in the subcortical white macter. 5111 symptomatic patients showed significantly higher ADC values even in the absence of periventricular interstitial edema (both groups contained patients with communicating and obstructive hydrocephalus). All 5 asymptomatic patients with hydrocephalus did not have a significantly higher ADC values in the periventricular region. Conclusion: In patients with hydrocephalus and acutely increased cerebral pressure. DWI showed a significantly hi-her ADC values in the periventricular region even without visible interstitial edema on conventional MRI sequences.

Item Type: Article
Uncontrolled Keywords: MAGNETIC-RESONANCE; HUMAN BRAIN; MR; MRI; DWI; apparent diffusion coefficient; hydrocephalus
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurochirurgie
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 21 Jun 2021 08:53
Last Modified: 21 Jun 2021 08:53
URI: https://pred.uni-regensburg.de/id/eprint/36823

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