Mohty, M. and Malard, F. and Abecassis, M. and Aerts, E. and Alaskar, A. S. and Aljurf, M. and Arat, M. and Bader, P. and Baron, F. and Bazarbachi, A. and Blaise, D. and Ciceri, F. and Corbacioglu, S. and Dalle, J-H and Dignan, F. and Fukuda, T. and Huynh, A. and Masszi, T. and Michallet, M. and Nagler, A. and NiChonghaile, M. and Okamoto, S. and Pagliuca, A. and Peters, C. and Petersen, F. B. and Richardson, P. G. and Ruutu, T. and Savani, B. N. and Wallhult, E. and Yakoub-Agha, I. and Duarte, R. F. and Carreras, E. (2016) Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation. BONE MARROW TRANSPLANTATION, 51 (7). pp. 906-912. ISSN 0268-3369, 1476-5365
Full text not available from this repository. (Request a copy)Abstract
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life threatening complication that can develop after hematopoietic cell transplantation. Although SOS/VOD progressively resolves within a few weeks in most patients, the most severe forms result in multi-organ dysfunction and are associated with a high mortality rate (480%). Therefore, careful attention must be paid to allow an early detection of SOS/VOD, particularly as drugs have now proven to be effective and licensed for its treatment. Unfortunately, current criteria lack sensitivity and specificity, making early identification and severity assessment of SOS/VOD difficult. The aim of this work is to propose a new definition for diagnosis, and a severity-grading system for SOS/VOD in adult patients, on behalf of the European Society for Blood and Marrow Transplantation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEPATIC VENOOCCLUSIVE-DISEASE; STEM-CELL TRANSPLANTATION; TISSUE-PLASMINOGEN ACTIVATOR; HIGH-RISK POPULATION; VERSUS-HOST-DISEASE; MR-IMAGING FINDINGS; CONDITIONING REGIMEN; VENOCCLUSIVE DISEASE; SIGNIFICANT TOXICITY; MULTIORGAN FAILURE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Apr 2019 13:04 |
| Last Modified: | 08 Apr 2019 13:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/3684 |
Actions (login required)
 |
View Item |
