Leone, M. and May, Arne and Franzini, A. and Broggi, G. and Dodick, D. and Rapoport, A. and Goadsby, P. J. and Schoenen, J. and Bonavita, V. and Bussone, G. (2004) Deep brain stimulation for intractable chronic cluster headache: proposals for patient selection. CEPHALALGIA, 24 (11). pp. 934-937. ISSN 0333-1024, 1468-2982
Full text not available from this repository.Abstract
Cluster headache is the most severe of the primary headaches. Positron emission tomography and functional MRI studies have shown that the ipsilateral posterior hypothalamus is activated during cluster headache attacks and is structurally asymmetric in these patients. These changes are highly specific for the condition and suggest that the cluster headache generator may be located in that brain area; they further suggest that electrical stimulation of that region might produce clinical improvement in chronic cluster headache sufferers refractory to medical therapy. In five patients with severe intractable chronic cluster headache, hypothalamic electrical stimulation produced complete and long-term pain relief with no relevant side-effects. We therefore consider it essential to propose criteria for selecting chronic cluster headache patients for hypothalamic deep brain stimulation before this procedure is undertaken at other academic medical centres.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HYPOTHALAMIC GRAY-MATTER; PAIN; PET; ACTIVATION; CAPSAICIN; MELATONIN; VERAPAMIL; CORTISOL; ATTACKS; SERIES; cluster headache; deep brain stimulation; therapy; surgery; hypothalamus |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Jun 2021 12:41 |
| Last Modified: | 22 Jun 2021 12:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36989 |
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