Herrmann, Wolfgang Artur and von Mohrenfels, Christoph Winkler and Lohmann, Chris Patrick (2004) Confocal microscopy and corneal sensitivity in a patient with corneal manifestations of Tangier disease. CORNEA, 23 (8). pp. 825-827. ISSN 0277-3740,
Full text not available from this repository. (Request a copy)Abstract
Purpose: Tangier disease is an autosomal recessive disorder in which cholesterol-rich lipids are deposited at various tissues of the body including the cornea. In this case report, the corneal changes in a patient with Tangier disease are described. Methods: A 72-year-old patient who was diagnosed with Tangier disease 25 years before received a complete eye examination including confocal microscopy and Cochet-Bonnet esthesiometry. Results: Slit-lamp biomicroscopy and confocal microscopy showed bilateral corneal opacifications caused by lipid accumulation. Confocal microscopy showed that pathologic changes in the cornea in Tangier disease are limited to the stroma. Neither a reduced corneal sensation nor lid abnormalities as previously described in Tangier disease were found. Conclusion: Confocal microscopy helps to identify corneal changes in the stroma caused by Tangier disease easily missed in a Slit-lamp examination. The ocular manifestations of Tangier disease do not necessarily include a reduced corneal sensitivity and lid abnormalities.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DENSITY-LIPOPROTEIN DEFICIENCY; Tangier disease; cortical opacification; corneal sensation; confocal microscopy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Augenheilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Jun 2021 13:54 |
| Last Modified: | 22 Jun 2021 13:54 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36992 |
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