Differences in cerebral glucose metabolism between frontotemporal lobar degeneration and Alzheimer's disease

Poljansky, Stefan and Ibach, Bernd and Vogel, Matthias and Maenner, Peter and Marienhagen, Joerg and Hajak, Goeran (2004) Differences in cerebral glucose metabolism between frontotemporal lobar degeneration and Alzheimer's disease. PSYCHIATRISCHE PRAXIS, 31. S73-S75. ISSN 0303-4259,

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Abstract

Objective: To describe differences in cerebral glucose metabolism between frontotemporal lobar degeneration (FTLD) and Alzheimer's disease (AD). Methods: 14 patients with FTLD (7 f/7 m, mean age 60.1 years) and 14 patients with AD (7 f/7 m, mean age 59.5 years) were examined. [18F]FDG positron emission tomography (PET) scans were analysed with statistical non-parametric mapping (SnPM) and statistical parametric mapping (SPM99). Results: Significant decreases in glucose metabolism in FTLD compared to AD were detected in the left insula/left inferior frontal gyrus (Brodman area [BA]13, 45 and 47) and in the medial frontal gyrus bilaterally (BA10). A significant decrease in AD compared to FTLD was identified in the right middle temporal gyrus (BA39). Conclusion: Cerebral PET could be a promising tool to discriminate FTLD from AD.

Item Type: Article
Uncontrolled Keywords: ;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Medicine > Abteilung für Nuklearmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 Jun 2021 10:06
Last Modified: 25 Jun 2021 10:06
URI: https://pred.uni-regensburg.de/id/eprint/37038

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