Consensus-recommendations for Sirolimus in liver transplantation

Golling, M. and Becker, T. and Broelsch, C. and Candinas, D. and Faust, D. and Fischer, L. and Geissler, Edward and Graeb, C. and Iberer, F. and Klupp, J. and Kraus, T. and Mueller, A. R. and Neuhaus, P. and Strassburg, CP and Wolff, M. and Zuelke, C. and Bechstein, Wolf O. (2004) Consensus-recommendations for Sirolimus in liver transplantation. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 42 (11). pp. 1333-1340. ISSN 0044-2771,

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Abstract

Sirolimus is an m-TOR inhibitor without renal side effects and potentially protects against the development of malignancy. Due to a higher incidence of complications in two trials and an official warning in the drug information, the use of Sirolimus in liver transplantation is limited. The participants of this consensus meeting had to analyse and evaluate the literature with respect to the potential role of Sirolimus in liver transplantation. This consensus statement follows the scheme normally employed for the presentation of guidelines including the grading of evidence (1a-5) and the extent of recommendation (A-C). Moreover, the consensus included the experience of the authors with respect to the handling of Sirolimus after liver transplantation.

Item Type: Article
Uncontrolled Keywords: EARLY CYCLOSPORINE WITHDRAWAL; CALCINEURIN INHIBITOR; RENAL-FUNCTION; KIDNEY-TRANSPLANTATION; CHRONIC REJECTION; INTERSTITIAL PNEUMONITIS; TUMOR PROGRESSION; RAPAMYCIN; RECIPIENTS; THERAPY; Sirolimus; liver transplantation; consensus conference
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 Jun 2021 12:23
Last Modified: 25 Jun 2021 12:23
URI: https://pred.uni-regensburg.de/id/eprint/37056

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