Gleich, Otto and Weiss, Marianne and Strutz, Jürgen (2004) Age-dependent changes in the lateral superior olive of the gerbil (Meriones unguiculatus). HEARING RESEARCH, 194 (1-2). pp. 47-59. ISSN 0378-5955,
Full text not available from this repository. (Request a copy)Abstract
Data from humans and animal models provide evidence for an age-dependent impairment in the ability to localize sound. The lateral superior olive (LSO) in the ascending auditory pathway is one important center involved in processing of binaural auditory stimuli. To identify potential age-dependent changes we characterized the LSO in young (< 15 months) and old ( greater than or equal to 3 years) gerbils with a special emphasis on the expression of GABA- and glycine-like immuno-reactivity. The dimensions of the LSO, as well as the number and density of glycine- and GABA-immuno-reactive neurons, were not significantly different between young and old gerbils. The size of glycine- and GABA-immuno-reactive neurons was significantly reduced in the high-frequency (medial) limb of the LSO. Over all, age-dependent changes in the LSO of the gerbil were small. (C) 2004 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AUDITORY BRAIN-STEM; COCHLEAR-NUCLEUS; GLYCINE IMMUNOREACTIVITY; INFERIOR COLLICULUS; TRAPEZOID BODY; MEDIAL NUCLEUS; GABA IMMUNOREACTIVITY; MONGOLIAN GERBIL; FISCHER-344 RAT; RHESUS-MONKEY; binaural hearing; aging; GABA; glycine; olivary complex; sound localization |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Jul 2021 10:08 |
| Last Modified: | 05 Jul 2021 10:08 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37393 |
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