Helfrich-Foerster, Charlotte (2004) The circadian clock in the brain: a structural and functional comparison between mammals and insects. JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 190 (8). pp. 601-613. ISSN 0340-7594, 1432-1351
Full text not available from this repository. (Request a copy)Abstract
The circadian master clocks in the brains of mammals and insects are compared in respect to location, organization and function. They show astonishing similarities. Both clocks are anatomically and functionally connected to the optic system and possess multiple output pathways allowing synchronization with the environmental light-dark cycles as well as the control of diverse endocrine, autonomic and behavioral functions. Both circadian master clocks are composed of multiple neurons, which are organized in populations with different morphology, physiology and neurotransmitter content and appear to subserve different functions. In the hamster and in the cockroach, the master clock consists of a core region that gets input from the eyes, and a shell region from which the majority of output projections originate. Communication between core and shell, between all other populations of clock neurons as well as between the master clocks of both brain hemispheres is a prerequisite of normal rhythmic function. Phenomena like rhythm splitting and internal desynchronization can be observed under constant light conditions and are caused by the "uncoupling" of the master clocks of both brain hemispheres.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PIGMENT-DISPERSING HORMONE; COCKROACH LEUCOPHAEA-MADERAE; RAT SUPRACHIASMATIC NUCLEUS; PER2 GENE-EXPRESSION; DROSOPHILA-MELANOGASTER; NERVOUS-SYSTEM; IMMUNOREACTIVE NEURONS; BEHAVIORAL RHYTHMS; ACCESSORY MEDULLA; OPTIC LOBE; accessory medulla; circadian rhythms; clock genes; neuropeptides; suprachiasmatic nucleus |
| Subjects: | 500 Science > 590 Zoological sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Zoologie > Alumni or Retired > Organisation der inneren Uhr auf neuronaler Ebene (Prof. Dr. Charlotte Förster) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 18 Jan 2022 10:41 |
| Last Modified: | 18 Jan 2022 10:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37398 |
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