Guba, Markus and Graeb, Christian and Jauch, Karl-Walter and Geissler, Edward K. (2004) Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation. TRANSPLANTATION, 77 (12). pp. 1777-1782. ISSN 0041-1337, 1534-6080
Full text not available from this repository. (Request a copy)Abstract
Development of cancer is a feared, and increasingly apparent, complication of long-term immunosuppressive therapy in transplant recipients. In addition to the need to reduce cancer occurrence in these patients, therapeutic protocols are lacking to simultaneously attack the malignancy and protect the allograft when neoplasms do occur. In this overview, we present the current literature regarding the pro- and anti-neoplastic effects of immunosuppressive agents on cancer growth and development. Recent experimental findings are paving the way for new therapeutic strategies aimed at both protecting an allograft from immunologic rejection and addressing the problem of cancer in this high-risk population.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ENDOTHELIAL GROWTH-FACTOR; KIDNEY-GRAFT RECIPIENTS; CYCLOSPORINE-A; RENAL-TRANSPLANTATION; LIVER-TRANSPLANTATION; TUMOR-GROWTH; HEPATOCELLULAR-CARCINOMA; MYCOPHENOLATE-MOFETIL; MEDICAL PROGRESS; KAPOSIS-SARCOMA; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Oct 2021 09:55 |
| Last Modified: | 14 Oct 2021 09:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37530 |
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