Brusch, L. and Cuniberti, Gianaurelio and Bertau, M. (2004) Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics. BIOPHYSICAL CHEMISTRY, 109 (3). pp. 413-426. ISSN 0301-4622,
Full text not available from this repository. (Request a copy)Abstract
Anaerobic glycolysis in yeast perturbed by the reduction of xenobiotic ketones is studied numerically in two models which possess the same topology but different levels of complexity. By comparing both models' predictions for concentrations and fluxes as well as steady or oscillatory temporal behavior we answer the question what phenomena require what kind of minimum model abstraction. While mean concentrations and fluxes are predicted in agreement by both models we observe different domains of oscillatory behavior in parameter space. Generic properties of the glycolytic response to ketones are discussed. (C) 2003 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SACCHAROMYCES-CEREVISIAE; BAKERS-YEAST; BIOCHEMICAL NETWORKS; REDUCTION; DYNAMICS; CALCIUM; ESTERS; GENE; TRANSDUCTION; ENZYMES; glycolysis; metabolic oscillations; model; biotransformation |
| Subjects: | 500 Science > 530 Physics |
| Divisions: | Physics > Institute of Theroretical Physics > Alumni or Retired Professors > Group Gianaurelio Cuniberti |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Jul 2021 05:26 |
| Last Modified: | 14 Jul 2021 05:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37559 |
Actions (login required)
 |
View Item |
