Piso, Pompiliu and Dahlke, Marc-Hendrik and Mirena, Petrit and Schmidt, Ursula and Aselmann, Heiko and Schlitt, Hans Juergen and Raab, Rudolf and Klempnauer, Juergen (2004) Total mesorectal excision for middle and lower rectal cancer: A single institution experience with 337 consecutive patients. JOURNAL OF SURGICAL ONCOLOGY, 86 (3). pp. 115-121. ISSN 0022-4790, 1096-9098
Full text not available from this repository. (Request a copy)Abstract
Background and Objectives: There have been reports on improved prognosis after TME for middle and lower rectal cancer. No prospective randomized studies have yet been performed. This is a large single institution series evaluating its own results of TME. Methods: This retrospective study analyses data of 337 patients with middle and lower rectal cancer, treated with either curative or palliative intention between 1990 and 1998. Results: Of all patients, 212 had lower rectal and 125 middle rectal carcinomas. The rate of rectal resections with TME was 96%. A total of 223 patients were treated by anterior rectal resection; 92 patients had to undergo abdomino-perineal resection. Ten patients were operated by a Hartmann resection. Postoperative morbidity was 35% with a leakage rate of 9%. Postoperative mortality was 4%. The rate of local recurrence was 8.6%. The 5-year survival rate after curative resection was 69.3%. The multivariate analysis outlined the tumor stage as independent prognostic factor. Conclusions: In our experience, TME is feasible with acceptable postoperative morbidity and low mortality. The local recurrence rate can be decreased to lower than 10%. The almost 70% 5-year survival rate indicates a clear benefit for the patients. These findings recommend TME as standard procedure for middle and lower rectal cancer. (C) 2004 Wiley-Liss, Inc.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LOW ANTERIOR RESECTION; COLOANAL ANASTOMOSIS; SURGICAL-TREATMENT; RECURRENCE; CARCINOMA; SURVIVAL; NETHERLANDS; SURGERY; 3RD; total mesorectal excision; rectal cancer; anterior rectal resection; abdomino-perineal resection |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Jul 2021 13:51 |
| Last Modified: | 19 Jul 2021 13:51 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37599 |
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