Stereoselective synthesis of novel conformationally restricted beta- and gamma-amino acids

Gnad, Frieder and Poleschak, Marko and Reiser, Oliver (2004) Stereoselective synthesis of novel conformationally restricted beta- and gamma-amino acids. TETRAHEDRON LETTERS, 45 (22). pp. 4277-4280. ISSN 0040-4039

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Abstract

Novel conformationally restricted beta- and gamma-amino acids containing a cyclopropane ring could be stereoselectively synthesized from readily available 5-methoxyindole and pyridine by copper(1)-catalyzed cyclopropanation with methyl diazoacetate followed by Subsequent oxidative cleavage of the resulting adducts. (C) 2004 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: AMINOCYCLOPROPANE-CARBOXYLIC-ACIDS; ENHANCED ANTIOPIATE ACTIVITY; HETEROCYCLIC SERIES; PEPTIDE MOLECULES; TASTE PROPERTIES; NEUROPEPTIDE-Y; ANALOGS; ALPHA; THIOSEMICARBAZONES; PEPTIDOMIMETICS; amino acids; cyclopropanes; peptidomimetics; catalysis; pyridines; indoles
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 20 Jul 2021 06:20
Last Modified: 20 Jul 2021 06:20
URI: https://pred.uni-regensburg.de/id/eprint/37637

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