Bonauer, Christoph and Zabel, Manfred and Koenig, Burkhard (2004) Synthesis and peptide binding properties of methoxypyrrole amino acids (MOPAS). ORGANIC LETTERS, 6 (9). pp. 1349-1352. ISSN 1523-7060, 1523-7052
Full text not available from this repository. (Request a copy)Abstract
Methoxypyrrole amino acids (MOPAS) have been prepared and were introduced into small peptides with hairpin structures. The intra- and intermolecular binding properties of this heterocyclic amino acid mimicking a dipeptido beta-strand was investigated by NMR titration and X-ray crystal structure analysis. The data reveal a hydrogen bonding pattern that is complementary to a peptide beta-sheet.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ARTIFICIAL BETA-SHEET; MOLECULAR SCAFFOLDS; ASYMMETRIC-SYNTHESIS; DESIGNED MOLECULES; HAIRPIN FORMATION; STRAND; STABILIZATION; PEPTIDOMIMETICS; RECOGNITION; NUCLEATION; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 21 Jul 2021 07:56 |
| Last Modified: | 21 Jul 2021 07:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37732 |
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