High-resolution contrast-enhanced magnetic resonance angiography of the carotid arteries using fluoroscopic monitoring of contrast arrival: Diagnostic accuracy and interobserver variability

Butz, B. and Dorenbeck, U. and Borisch, I. and Zorger, N. and Lenhart, M. and Feuerbach, S. and Link, J. (2004) High-resolution contrast-enhanced magnetic resonance angiography of the carotid arteries using fluoroscopic monitoring of contrast arrival: Diagnostic accuracy and interobserver variability. ACTA RADIOLOGICA, 45 (2). pp. 164-170. ISSN 0284-1851, 1600-0455

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Abstract

Purpose: To evaluate the diagnostic accuracy of high-resolution contrast-enhanced magnetic resonance angiograpby (CE-MRA) of the supra-aortic arteries using the CareBolus technique. Digital subtraction angiography was the standard of reference. Material and Methods: Fifty consecutive patients with suspected internal carotid artery stenosis underwent CE-MRA and digital subtraction angiography. CE-MRA was performed on a 1.5-T superconducting scanner with the CareBolus technique. CareBolus combines a nearly real-time 2D-FLASH (fast low angle shot) sequence for fluoroscopic triggering and a high-resolution 3D-FLASH with elliptical centric view order for the angiographic Pulse sequence (6.0/2.16 ms [TR/TE], 30degrees flip angle, 30.98 s acquisition time, 0.88 mm effective (interpolated) partition thickness and a 160 x 512 matrix). Intra-arterial digital subtraction angiography and CE-MRA studies were evaluated independently by four blinded readers. Internal carotid artery stenoses were graded according to the NASCET criteria. Results: CE-MRA had an accuracy of 92.53%, a sensitivity of 95.64%, and a specificity of 90.39% for the identification of carotid artery stenoses greater than or equal to 70% (grade 3). Image quality for suppression of stationary tissue and venous contrast was good, but was reduced in five cases due to patient motion. Conclusion: The CareBolus technique is a useful non-invasive method for high-resolution imaging of the supra-aortic vessels because of its easy application and high sensitivity and specificity. Limitations can occur in non-compliant patients due to motion artifacts during the measurement time.

Item Type: Article
Uncontrolled Keywords: DIGITAL-SUBTRACTION-ANGIOGRAPHY; X-RAY ANGIOGRAPHY; MR-ANGIOGRAPHY; CONVENTIONAL ANGIOGRAPHY; STENOSIS; ENDARTERECTOMY; ULTRASOUND; AGREEMENT; DSA; angiography; elliptic centric view ordering; magnetic resonance imaging; supra-aortic arteries
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 21 Jul 2021 10:09
Last Modified: 21 Jul 2021 10:09
URI: https://pred.uni-regensburg.de/id/eprint/37756

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