Zorger, Niels and Finkenzeller, Thomas and Lenhart, Markus and Hamer, Okka and Paetzel, Christian and Borisch, Inghita and Toepel, Ingolf and Feuerbach, Stefan and Link, Johann (2004) Safety and efficacy of the Perclose suture-mediated closure device following carotid artery stenting under clopidogrel platelet blockade. EUROPEAN RADIOLOGY, 14 (4). pp. 719-722. ISSN 0938-7994,
Full text not available from this repository. (Request a copy)Abstract
The aim of this study was evaluation of a closure device (Perclose, Menlo Park, Calif.) for closure of the femoral artery access site in patients undergoing aggressive anticoagulation and platelet blockade after carotid stenting. Fifty-five patients who received clopidogrel in addition to aspirin and heparin as medication for carotid stenting were included for suture of the femoral access site after using 7- or 8-F guide catheters. The technical success, the time for suture, the clotting parameters, and complications were examined. Follow-up investigations, including ultrasound and clinical examinations, were performed. The groin was checked for possible hematoma, pseudoaneurysm, arteriovenous fistula, and local infection. Technical success was obtained in 51 of 54 patients (94%) after a mean procedure time of 6 min (range 5-10 min). The suture device was not used in one patient (2%) for anatomical reasons and failed to obtain hemostasis in 3 of 54 (6%) patients. In 4 of 54 patients (7%) bleeding was observed at the punctured site 4-6 h after intervention which was treated by a compression bandage. The mean dedicated activated clotting time was 137 s (range 29-287 s) before intervention and 349 s (150-958 s) just before deploying the Perclose device. During follow-up after 2 days (range 2-6 days) and 6 months no further complications of the puncture site were observed except for two large groin hematomas. No major complications occurred. Closure of the femoral access site after carotid stenting using a Perclose closure device is safe and effective even in patients receiving an aggressive anticoagulation and antiplatelet therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | VASCULAR COMPLICATIONS; CARDIAC-CATHETERIZATION; FEMORAL-ARTERY; INTERVENTIONS; ANGIOPLASTY; MANAGEMENT; PUNCTURE; SITE; femoral arteries; catheters and catheterization; percutaneous closure devices; angioplasty; carotid artery |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Jul 2021 05:21 |
| Last Modified: | 26 Jul 2021 05:21 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37778 |
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