Tandon, Vishnu K. and Chhor, Rakeshwar B. and Singh, Ravindra V. and Rai, Sanjay and Yadav, Dharmendra B. (2004) Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 14 (5). pp. 1079-1083. ISSN 0960-894X, 1464-3405
Full text not available from this repository. (Request a copy)Abstract
A series of 1,4-naphthoquinone derivatives were synthesized and tested for antifungal and antitumor activity against a number of fungal disease causative species and Walker 256 carcinoma cell lines. The results show that the compounds 8a,e and 11b possess pronounced antifungal proifile where as 7b and f were found to be active against Walker 256 carcinoma cell lines. Moreover 7c and 11a showed inhibitory effect against reverse transcriptase enzyme from Rauscher Murine Leukemia Virus. (C) 2004 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CELLS; ANALOGS; antifungal; anticancer; 1,4-napthoquinone derivatives; antifungal drugs; carcinoma cell lines |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Jul 2021 09:55 |
| Last Modified: | 22 Jul 2021 09:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/37886 |
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