Synthesis of naturally occurring pyrazine and imidazole alkaloids from Botryllus leachi

Mahboobi, Siavosh and Sellmer, Andreas and Burgemeister, Thomas and Lyssenko, Alexei and Schollmeyer, Dieter (2004) Synthesis of naturally occurring pyrazine and imidazole alkaloids from Botryllus leachi. MONATSHEFTE FUR CHEMIE, 135 (3). pp. 333-342. ISSN 0026-9247, 1434-4475

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Abstract

The synthesis of the naturally occurring and biologically active alkaloids 1 and 2, first isolated from the red ascidian Botryllus leachi by Duran et al. [1], is described and the structure proposed for Botryllazine B (1) is confirmed. The analytical data for 2-(p-hydroxybenzoyl)-4-(p-hydroxyphenyl)imidazole (2) are discussed and compared with the literature. With special emphasis of H-1 NMR data the tautomerism of aroylimidazolemethanones is described.

Item Type: Article
Uncontrolled Keywords: pyrazine and imidazole alkaloids; annular tautomers; Botryllus leachi; biologically active compounds
Subjects: 500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Divisions: Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 22 Jul 2021 10:12
Last Modified: 22 Jul 2021 10:12
URI: https://pred.uni-regensburg.de/id/eprint/37948

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