Clinical utility of the cardiac markers BNP and NT-proBNP

Buchner, Stefan and Riegger, G. and Luchner, A. (2004) Clinical utility of the cardiac markers BNP and NT-proBNP. ACTA MEDICA AUSTRIACA, 31 (4). pp. 144-151. ISSN 0303-8173

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Abstract

BNP and NT-proBNP are new markers with potential applications for the diagnosis and management of patients with cardiovascular diseases. In patients with acute dyspnea, these markers might strengthen the clinical suspicion of decompensated congestive heart failure. Vice versa, below-threshold marker concentrations allow to virtually exclude significant left ventricular dysfunction in symptomatic patients. Furthermore, BNP and NT-proBNP are predictors of morbidity and mortality in patients with heart failure, but also in acute coronary syndrome, myocardial infarction, pulmonary embolism and other cardiovascular diseases. The markers therefore appear suitable for additional risk stratification. Independently from the clinical application, however, it is important to note that extracardiac variables may affect marker concentrations and need to be considered when marker concentrations are interpreted. Due to their diagnostic and prognostic value, the cardiac markers BNP and NT-proBNP have a clear potential to further improve the care of patients with cardiovascular diseases.

Item Type: Article
Uncontrolled Keywords: BRAIN NATRIURETIC PEPTIDE; ACUTE PULMONARY-EMBOLISM; CHRONIC HEART-FAILURE; LEFT-VENTRICULAR HYPERTROPHY; CORONARY-ARTERY-DISEASE; TRIAL VAL-HEFT; MYOCARDIAL-INFARCTION; EMERGENCY DIAGNOSIS; RISK STRATIFICATION; DYSFUNCTION; BNP; natriuretic peptides; congestive heart failure (CHF); markers; myocardial infarction; risk stratification; prognosis
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Petra Gürster
Date Deposited: 21 Jul 2021 08:56
Last Modified: 21 Jul 2021 08:56
URI: https://pred.uni-regensburg.de/id/eprint/38091

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