Insulin resistance in patients with polycystic ovary syndrome

Schroeder, Annika K. and Tauchert, Sascha and Ortmann, Olaf and Diedrich, Klaus and Weiss, Jürgen M. (2004) Insulin resistance in patients with polycystic ovary syndrome. ANNALS OF MEDICINE, 36 (6). pp. 426-439. ISSN 0785-3890, 1365-2060

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Abstract

With a prevalence of 5%-10% the polycystic ovary syndrome (PCOS) is an exceptionally common disorder of premenopausal women. According to prospective studies, women with PCOS present abnormal glucose tolerance and diabetes mellitus in 31%-35% and 7.5%-10%, respectively. PCOS patients have a higher prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes and dyslipidaemia. The rate of spontaneous abortions as well as the risk to develop gestational or type 2 diabetes is increased in PCOS. Therefore, PCOS is not only a reproductive problem but a complex endocrine disease with important health implications. The role of the glucose metabolism in PCOS, the health consequences and possible interventions are reviewed in this article.

Item Type: Article
Uncontrolled Keywords: IMPAIRED GLUCOSE-TOLERANCE; DEPENDENT DIABETES-MELLITUS; CORONARY-ARTERY-DISEASE; METFORMIN THERAPY IMPROVES; HORMONE-BINDING GLOBULIN; PLACEBO-CONTROLLED TRIAL; IN-VITRO FERTILIZATION; BETA-CELL DYSFUNCTION; TERM-FOLLOW-UP; OBESE WOMEN; diabetes; insulin; insulin resistance; PCOS; polycystic ovary syndrome; review; risk
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Depositing User: Petra Gürster
Date Deposited: 20 Jul 2021 10:19
Last Modified: 20 Jul 2021 10:19
URI: https://pred.uni-regensburg.de/id/eprint/38110

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