Bandichhor, Rakeshwar and Singh, Kunwar and Nosse, Bernd and Tandon, Vishnu K. (2004) Synthesis and anti-implantation activity of new stilbene derivatives. ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 54 (8). pp. 452-455. ISSN 0004-4172, 1616-7066
Full text not available from this repository. (Request a copy)Abstract
New stilbene (CAS 56-53-1) derivatives have been synthesized by reductive elimination of desoxybenzoin analogs which were obtained by Fries rearrangement of the corresponding phenolic esters. The chemical structures of the compounds obtained were confirmed by H-1-NMR, IR and elemental analysis. Anti-implantation activity of the compounds was determined by performing experiments with adult male and female Spargue-Dawley rats of proven fertility. A 67 % inhibition of implantation was observed separately with compounds 3f and 3i.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ESTROGEN-RECEPTOR MODULATORS; CANCER; CAS 56-53-1; estrogens, synthetic; stilbene, anti-implantation activity, derivatives; stereo-selectivity, synthesis |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 Aug 2021 11:36 |
| Last Modified: | 03 Aug 2021 11:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38117 |
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