Synthesis and anti-implantation activity of novel non-steroidal 4,5-disubstituted 2 31415-tetrahydro-1-benzoxepines

Rai, Sanjay and Tandon, Vishnu K. (2004) Synthesis and anti-implantation activity of novel non-steroidal 4,5-disubstituted 2 31415-tetrahydro-1-benzoxepines. ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 54 (12). pp. 887-890. ISSN 0004-4172, 1616-7066

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Abstract

The synthesis and anti-implantation activity of some novel 4,5-disubstiuted 2,3,4,5-tetrahydro-1-benzoxepins are presented. The synthesized compounds were evaluated for their anti-implantation activity in mature female Sprague-Dawley rats. The antifertility activity, as assessed by post coital anti-implantation test, was of weak potency for most of the compounds. Compounds 9d and 10d exhibited the highest anti-implantation activity among the tested compounds.

Item Type: Article
Uncontrolled Keywords: ANTIFERTILITY AGENTS; benzoxepines, antifertility, activity; anti-implantation activity; contraceptives; non-steroidal; estrogen
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 03 Aug 2021 11:40
Last Modified: 03 Aug 2021 11:40
URI: https://pred.uni-regensburg.de/id/eprint/38118

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