Djavidani, Behrus and Schmid, Franz X. and Keyser, Andreas and Butz, Bernhard and Seitz, Johannes and Luchner, Andreas and Debl, Kurt and Feuerbach, Stefan and Nitz, Wolfgang R. (2004) Early regression of left ventricular hypertrophy after aortic valve 14 replacement by the ross procedure detected by Cine MRI. JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, 6 (1). pp. 1-8. ISSN 1097-6647
Full text not available from this repository. (Request a copy)Abstract
Aim. The primary objective of our study was to assess the time course of left ventricular remodeling after the Ross procedure with the use of cine magnetic resonance imaging (MRI). Methods. In a prospective study, 10 patients with isolated aortic valve disease were examined prior to aortic valve surgery, as well as at early follow-up (mean 4 weeks) and at late follow-up (mean 8 months) after pulmonary autograft aortic valve replacement (Ross procedure). The heart was imaged with a 1.5 T MR scanner along the short and long axes using a breath-hold, electrocardiogram (ECG)-triggered, cine gradient-echo sequence (FLASH). Myocardial mass and ventricular function were assessed. Results. After aortic valve replacement, left ventricular myocardial mass (LVM) decreased by 13% (261+/-74 g to 230+/-65 g, p<0.05) in the early postoperative period and by a further 16% in the late postoperative period to 192 31 g (p<0.05). In addition, left ventricular end-diastolic and end-systolic volumes decreased from preoperative 187+/-89 mL (LV EDV) and 73+/-59 mL (LV ESV) to 119+/-55 mL and 56+/-42 mL, respectively, in the early postoperative period. In the late postoperative period, there was a further decrease to 98+/-30 (p<0.05) and 33+/-19 mL, respectively. Ejection fraction did not change markedly after surgery (preoperatively 61+/-13% vs. 56+/-14% postoperatively). Patients with leading aortic stenosis were characterized by predominant regression of LVM and patients with leading aortic regurgitation by predominant regression of LV EDV (each p<0.05). Conclusion. Cine MRI allows accurate assessment of left ventricular structure and geometry before and after aortic valve replacement with pulmonary autograft and is very sensitive in detecting relatively small changes of left ventricular myocardial mass and volumes early after hemodynamic relief as well as during serial assessment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AORTIC-VALVE REPLACEMENT; PULMONARY AUTOGRAFT; MAGNETIC-RESONANCE; CHILDREN; ROOT; MASS; REGURGITATION; STENOSIS; DISEASE; heart; aortic valve disease; Ross procedure; cine MRI; left ventricular hypertrophy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie Medicine > Lehrstuhl für Innere Medizin II Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 04 Aug 2021 08:52 |
| Last Modified: | 04 Aug 2021 08:52 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38184 |
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