Therapy and prophylaxis of cluster headache and other trigemino-autonomic cephalgias

May, A. and Evers, S. and Straube, A. and Pfaffenrath, V. and Diener, H. C. (2004) Therapy and prophylaxis of cluster headache and other trigemino-autonomic cephalgias. NERVENHEILKUNDE, 23 (8). 478-ff.. ISSN 0722-1541

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Abstract

Following the new HIS-classification, cluster headache, paroxysmal hemicrania and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT syndrome) are included into the classification as trigemino-autonomic cephalgias (TAC). The similarites of these syndromes suggest a considerably shared pathophysiology. These syndromes have in common that they involve activation of trigeminovascular nociceptive pathways with reflex cranial autonomic activation. Clinically, this physiology predicts pain with some combination of lacrimation, conjunctival injection, nasal congestion, or eyelid oedema. Broadly the management of TAC's comprises acute and prophylactic treatment. Some types of trigemino-autonomic headaches, such as paroxysmal hemicrania and hemicrania continua have, unlike cluster headaches, a very robust response to Indometacin, leading to a consideration of indometa-cin-sensitive headaches. This review covers the clinical picture and therapeutic options. Although studies following the criteria of evidence based medicine (EBM) are rare, most patients can be treated sufficiently.

Item Type: Article
Uncontrolled Keywords: CHRONIC PAROXYSMAL HEMICRANIA; SUNCT-SYNDROME; DOUBLE-BLIND; SUBCUTANEOUS SUMATRIPTAN; CLINICAL MANIFESTATIONS; ORAL ZOLMITRIPTAN; SODIUM VALPROATE; HYPNIC HEADACHE; TIC SYNDROME; FOLLOW-UP; trigemino-autonomic cephalgias; cluster headache; treatment; EBM-criteria
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurologie
Depositing User: Petra Gürster
Date Deposited: 15 Jul 2021 07:01
Last Modified: 15 Jul 2021 07:01
URI: https://pred.uni-regensburg.de/id/eprint/38223

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