Serotonin transporter gene polymorphism and personality traits in primary alcohol dependence

Wiesbeck, G. A. and Weijers, H. G. and Wodarz, Norbert and Keller, H. K. and Michel, T. M. and Herrmann, M. J. and Boening, J. (2004) Serotonin transporter gene polymorphism and personality traits in primary alcohol dependence. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 5 (1). pp. 45-48. ISSN 1562-2975

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Abstract

We tested the hypothesis of an association between the serotonin transporter (5-HTT) gene regulatory region polymorphism and the Temperament and Character Inventory (TCI) personality dimension of Harm Avoidance. For the study, 124 subjects seeking inpatient treatment for primary alcohol dependence were grouped by their 5-HTT genotype and assessed with the TCI. Genotypes differed statistically significantly in Harm Avoidance but not in any other personality trait. This gives support to the hypothesis that the TCI temperament Harm Avoidance is associated with serotonergic neuro-transmission in primary alcohol dependence.

Item Type: Article
Uncontrolled Keywords: REGULATORY REGION; TEMPERAMENT; ASSOCIATION; serotonin transporter (5-HTT) gene regulatory region polymorphism; Temperament and Character Inventory (TCI); harm avoidance; primary alcohol dependence
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 10 Aug 2021 10:49
Last Modified: 10 Aug 2021 10:49
URI: https://pred.uni-regensburg.de/id/eprint/38287

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