Butz, Bernhard and Strotzer, M. and Manke, C. and Roider, J. and Link, J. and Lenhart, M. (2003) Selective intraarterial fibrinolysis of acute central retinal artery occlusion. ACTA RADIOLOGICA, 44 (6). pp. 680-684. ISSN 0284-1851
Full text not available from this repository.Abstract
Purpose: To evaluate the outcome of our patients with central retinal artery occlusion after local fibrinolysis and to compare these data with results reported in the literature. Material and Methods: Over a period of 7 years, 22 patients (11 male, 11 female, mean age 64.6 +/- 12.1 years) were treated with super-selective local fibrinolysis. In 1 case, treatment was carried out via the maxillary-ophthalmic anastomoses due to preexisting occlusion of the ipsilateral internal carotid artery. The latency period from the onset of symptoms to the beginning of therapy was 7.6 +/- 1.8 h. Urokinase was used in 7 cases (300,000-1.1 million units) and recombinant tissue plasminogen activator (20-40 mg) was applied in 15 patients. Visual acuity and fundus were examined before and after treatment. Results: One patient (1/22 = 4.6%) recovered completely and regained a visual acuity of 20/20. Six patients (6/22 = 27.3%) showed a marked improvement with a range of visual outcome from 20/800 to 20/320. In 2 cases (2/22 = 9.1%) only a slight improvement was observed, with a visual outcome allowing detection of hand movements. In 13 cases (13/22 = 59.1%) no change in visual acuity as a result of treatment was observed. In 2/22 cases (9.2%) reversible neurological side-effects occurred, in 1 case suffered a stroke, and in another case intracerebral bleeding was observed. Conclusion: In our study, the recovery of visual acuity and the complication rate were not as positive as reported in the literature.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TISSUE-PLASMINOGEN-ACTIVATOR; THERAPY; THROMBOLYSIS; STROKE; central retinal artery occlusion; intraarterial fibrinolysis; interventional neuroradiology |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Aug 2021 05:32 |
| Last Modified: | 30 Aug 2021 05:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38423 |
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