Waters, E. and Hohn, M. J. and Ahel, I. and Graham, D. E. and Adams, M. D. and Barnstead, M. and Beeson, K. Y. and Bibbs, L. and Bolanos, R. and Keller, M. and Kretz, K. and Lin, X. Y. and Mathur, E. and Ni, J. W. and Podar, M. and Richardson, T. and Sutton, G. G. and Simon, M. and Soell, D. and Stetter, Karl O. and Short, J. M. and Noordewier, M. (2003) The genome of Nanoarchaeum equitans: Insights into early archaeal evolution and derived parasitism. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100 (22). pp. 12984-12988. ISSN 0027-8424
Full text not available from this repository.Abstract
The hyperthermophile Nanoarchaeum equitans is an obligate symbiont growing in coculture with the crenarchaeon Ignicoccus. Ribosomal protein and rRNA-based phylogenies place its branching point early in the archaeal lineage, representing the new archaeal kingdom Nanoarchaeota. The N. equitans genome (490,885 base pairs) encodes the machinery for information processing and repair, but lacks genes for lipid, cofactor, amino acid, or nucleotide biosyntheses. It is the smallest microbial genome sequenced to date, and also one of the most compact, with 95% of the DNA predicted to encode proteins or stable RNAs. Its limited biosynthetic and catabolic capacity indicates that N. equitans' symbiotic relationship to Ignicoccus is parasitic, making it the only known archaeal parasite. Unlike the small genomes of bacterial parasites that are undergoing reductive evolution, N. equitans has few pseudogenes or extensive regions of noncoding DNA. This organism represents a basal archaeal lineage and has a highly reduced genome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSFER-RNA GENES; REVERSE GYRASE; ENDOSYMBIOTIC BACTERIA; PHYLUM NANOARCHAEOTA; PROTEIN; SEQUENCE; DATABASE; HYPERTHERMOPHILE; DNA; IDENTIFICATION; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Mikrobiologie (Archaeenzentrum) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Jul 2021 13:15 |
| Last Modified: | 27 Jul 2021 13:15 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38509 |
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