Eichhammer, Peter and Langguth, Berthold and Marienhagen, Joerg and Kleinjung, Tobias and Hajak, Goeran (2003) Neuronavigated repetitive transcranial magnetic stimulation in patients with tinnitus: A short case series. BIOLOGICAL PSYCHIATRY, 54 (8). pp. 862-865. ISSN 0006-3223, 1873-2402
Full text not available from this repository.Abstract
Background: Clinical as well as neurophysiological and neuroimaging data suggest that chronic tinnitus resembles neuropsychiatric syndromes characterized by focal brain activation. Low-frequency repetitive transcranial magnetic stimulation (rTMS) has been proposed as an efficient method in treating brain hyperexcitability disorders by reducing cortical excitability. Methods: In three patients suffering from chronic tinnitus, the effect of magnetic resonance imaging and positron emission tomography guided neuronavigated 1 Hz rTMS on auditory cortex activity was evaluated, using a sham controlled double-blind crossover design. Results: Two of three patients revealed clearly increased metabolic activity in circumscript areas of the primary auditory cortex (PAC), allowing a selective stimulation of these cortical areas with low-frequency rTMS. Considerable improvement in tinnitus was achieved in these patients. Conclusions: Neuronavigated rTMS of increased PAC activity may help to better understand the neuronal basis of chronic tinnitus and might offer a new option for treating auditory phantom perceptions like chronic tinnitus. (C) 2003 Society of Biological Psychiatry.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MOTOR CORTEX EXCITABILITY; AUDITORY-CORTEX; TMS; neuronavigated transcranial magnetic stimulation; auditory phantom perception; chronic tinnitus; auditory hallucinations; positron emission tomography; magnetic resonance imaging |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde Medicine > Lehrstuhl für Psychiatrie und Psychotherapie Medicine > Abteilung für Nuklearmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Aug 2021 07:24 |
| Last Modified: | 30 Aug 2021 07:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38514 |
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