Gallmeier, Hans-Christoph and Koenig, Burkhard (2003) Heteroaromatic oligoamides with dDNA affinity. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (18). pp. 3473-3483. ISSN 1434-193X, 1099-0690
Full text not available from this repository.Abstract
Heteroaromatic oligoamides are selective ligands for sequence-specific dDNA binding, many artificial oligoamides modeled on naturally occurring compounds and their dDNA binding motifs having been prepared over the last ten years. The large number of reported individual compounds does not allow each structure to be covered within the scope of this review, so we concentrate on examples of the most successful linear and tethered oligoamide structures, such as hairpin, H- pin, or cyclic structures, and the ensemble of heteroaromatic amino acids used as their building blocks. This provides an overview of which chemical structures are currently in use for sequence-specific dDNA recognition by artificial ligands and what they can achieve. (C) Wiley-VCH Verlag GmbH Co.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DNA MINOR-GROOVE; SEQUENCE-SPECIFIC RECOGNITION; CROSS-LINKED LEXITROPSINS; SOLID-PHASE SYNTHESIS; DOUBLE-HELICAL DNA; PYRROLE-IMIDAZOLE POLYAMIDES; NETROPSIN-LIKE MOLECULES; ANTITUMOR AGENT CC-1065; COVALENT PEPTIDE DIMERS; BASE-PAIR SEQUENCES; DNA binding; heterocycles; molecular recognition; oligoamides |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Petra Gürster |
| Date Deposited: | 08 Jul 2021 09:03 |
| Last Modified: | 08 Jul 2021 09:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38606 |
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