Plikat, Katharina and Glueck, Thomas and Volk, Markus and Schoelmerich, Juergen (2003) 28-year-old patient with elevated serum IgE levels and multiple refractory epidural and paravertebral abscesses. Clinical manifestation of a Job's syndrome? MEDIZINISCHE KLINIK, 98 (9). pp. 534-538. ISSN 0723-5003
Full text not available from this repository. (Request a copy)Abstract
Background: The hyper-IgE syndrome is a rare primary immunodeficiency characterized by recurrent staphylococcal infections and high levels of serum IgE. Case Report: The case of a 28-year-old man with epidural and paravertebral abscesses and a markedly elevated serum IgE level of 2,609 U/ml is reported. There was no allergic diathesis, nor had the patient a history of other diseases, which might explain the high serum IgE level. In a blood culture, Staphylococcus aureus was detected. Since early childhood, the patient has suffered from recurrent skin infections. Conclusion: The presented study case discusses the diagnosis of a job's syndrome in this patient and reviews previously published cases. It also summarizes the current knowledge about pathogenesis and diagnostic criteria of this rare syndrome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HYPER-IGE; HYPERIMMUNOGLOBULINEMIA-E; INTERFERON-GAMMA; INTERLEUKIN-4; INFECTIONS; CYTOKINE; ALPHA; CELLS; Job's syndrome; hyper-IgE syndrome; Buckley syndrome; Staphylococcus aureus infection; chronic abscesses |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Sep 2021 06:33 |
| Last Modified: | 01 Sep 2021 06:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38607 |
Actions (login required)
 |
View Item |
