Scoccianti, Chiara and Cecchini, Michele and Anderson, Annie S. and Berrino, Franco and Boutron-Ruault, Marie-Christine and Espina, Carolina and Key, Timothy J. and Leitzmann, Michael and Norat, Teresa and Powers, Hilary and Wiseman, Martin and Romieu, Isabelle (2016) European Code against Cancer 4th Edition: Alcohol drinking and cancer. CANCER EPIDEMIOLOGY, 45. pp. 181-188. ISSN 1877-7821, 1877-783X
Full text not available from this repository. (Request a copy)Abstract
Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%-13%) of all cancer cases in men and 3% (95% CI: 1%-5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: "If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention." (C) 2015 International Agency for Research on Cancer; Licensee Elsevier Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POSTMENOPAUSAL BREAST-CANCER; AERODIGESTIVE TRACT CANCER; MTHFR C677T POLYMORPHISM; SQUAMOUS-CELL CARCINOMA; COLORECTAL-CANCER; POOLED ANALYSIS; UNITED-STATES; NECK-CANCER; METHYLENETETRAHYDROFOLATE REDUCTASE; HEPATOCELLULAR-CARCINOMA; Alcohol drinking; Cancer; Ethanol; Acetaldehyde; Disease; Primary prevention; Europe |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 10 Apr 2019 08:23 |
| Last Modified: | 10 Apr 2019 08:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/3870 |
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