de Jesus, O and Smith, PR and Spender, LC and Karstegl, CE and Niller, HH and Huang, D and Farrell, PJ (2003) Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV. JOURNAL OF GENERAL VIROLOGY, 84. pp. 1443-1450. ISSN 0022-1317,
Full text not available from this repository.Abstract
Two sequences required for activity of the Epstein-Barr virus BART RNA promoter in transfection assays have been identified by site-directed mutagenesis. One contains a consensus AP-1 site; the other has some similarity to Ets and Stat consensus binding sites. Candidate sequences were suggested by mapping a region of unmethylated DNA in EBV around the BART promoter followed by in vivo footprinting the promoter in the C666-1 nasopharyngeal carcinoma cell line, which expresses BART RNAs. The data are presented in the context of a revised EBV DNA sequence, known as EBV wt, that is proposed as a future standard sequence for EBV.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NASOPHARYNGEAL CARCINOMA; PROTEIN INTERACTS; GENE-EXPRESSION; CPG METHYLATION; B-CELLS; BAMHI; TRANSCRIPTS; LATENCY; FRAGMENT; BINDING; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 May 2021 10:44 |
| Last Modified: | 18 May 2021 10:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/38964 |
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