Przkora, Rene and Vogel, P. and Knuechel, R and Jauch, K. W. and Bolder, U. (2003) Synovial sarcoma in clinical practice - Description of selected cases. ZENTRALBLATT FUR CHIRURGIE, 128 (3). pp. 239-243. ISSN 0044-409X, 1438-9592
Full text not available from this repository. (Request a copy)Abstract
Clinically, synovial sarcoma becomes apparent as a growing mass. Initial presentation and the course may be variable. We discuss 4 characteristic patients. Case 1: A 37 year-old female patient presented with a mass in her thigh after two consecutive resections of a malignant hemangio-endothelioma. Histology: Biphasic synovial sarcoma (G II). Case 2: A tumor was enucleated in the adductors of a 42 year-old female patient. Histology: Biphasic synovial sarcoma (G I). 2 years later local tumor recurrence (G I) occurred. Treatment was provided by wide resection and radiotherapy. Case 3: Resection of a suspected neurinoma in the thigh of a 34 year-old male patient. Histology: Biphasic synovial sarcoma, positive margins. Case 4: A 74 year-old female patient receiving anticoagulants was symptomatic due to intracranial tumor hemorrhage of a metastasis of a previously unknown synovial sarcoma of her popliteal fossa. The primary tumor was initially misdiagnosed as Baker's cyst, causing a deep vein thrombosis. Histology: Angioinvasive synovial sarcoma (G II). Survival: 11 months. Therapy: Wide resection and postoperative irradiation in cases 1-3. Indication for the irradiation in case 2 and 3 was due to the inadaequate operation. An amputation was performed in case 4 because of infiltration of the neurovascular structures. Conclusion: The presentation of synovial sarcoma does not differ from other soft tissue sarcomas. Patients should be treated in specialized centers to reduce inadaequate operations. Outcome and rate of metastatic disease suggest the need for improved adjuvant treatment modalities.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SOFT-TISSUE SARCOMA; LONG-TERM SURVIVAL; PROGNOSTIC FACTORS; SYT; FUSION; SSX; IDENTIFICATION; MULTIVARIATE; EXTREMITY; TUMORS; synovial sarcoma; translocation; histology; metastasis; (neo)adjuvant therapy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Sep 2021 06:35 |
| Last Modified: | 20 Sep 2021 06:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/39271 |
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