Krueger, Bernd and Zuelke, Carl and Fischereder, Michael and Leingaertner, Tobias and Kammerl, Martin and Fuerst, Alois and Graeb, Christian and Anthuber, Matthias and Jauch, Karl-Walter and Kraemer, Bernhard K. (2002) Early experience with the ET Senior Program "Old For Old"; better to be number one? TRANSPLANT INTERNATIONAL, 15 (11). pp. 541-545. ISSN 0934-0874
Full text not available from this repository.Abstract
Eurotransplant offers a Senior Program to extend the donor pool for renal transplantation. The study comprised 14 patients of the ET Senior ("Old For Old") Program. Kidneys from five cadaveric donors were transplanted in pairs to ten recipients with a difference in cold ischemia time (CIT) of > 4 h, and grouped according to CIT (group 1: patients that underwent transplantation first; group 2: patients that underwent transplantation second). CIT was shorter (5.5 +/- 2.0 h vs. 11.7 +/- 3.1 h, P < 0.01), and the first day diuresis was higher (287.4 ml/h vs. 134.8 ml/h, P < 0.05) in group I than in group 2. No patient in group I required dialysis, 3/5 patients in group 2. Rejection episodes occured more often in group 2 (515 vs. 3/5), and the hospital stay tended to be shorter in group 1 (33.0 days (27-43) vs. 54.2 days (27-112)). Our study confirms the positive effect of ultra-short CIT on early graft function in marginal donors, despite overall short CIT. The increase in delayed graft function (DGF) may lead to an extended hospital stay and dialysis requirements. Efforts to realize simultaneous transplantation in two recipients seem necessary to optimize results.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GRAFT FUNCTION; TRANSPLANTS; KIDNEYS; AGE; ET senior program; cold ischemia time; kidney transplantation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 04 Oct 2021 06:56 |
| Last Modified: | 04 Oct 2021 06:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/39763 |
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