Hehlgans, Thomas and Maennel, Daniela N. (2002) The TNF-TNF receptor system. BIOLOGICAL CHEMISTRY, 383 (10). pp. 1581-1585. ISSN 1431-6730
Full text not available from this repository.Abstract
Different forms of tumor necrosis factor (TNF) interact with two specific receptors for TNF (TNFR) on the cell membrane to induce a variety of effects. While sharing structural similarities in their extracellular domains, the two TNFRs differ in their intracellular domain, their signal transduction, and consequently their function. In addition, one of the two TNFRs can be expressed in two differently located isoforms. This makes the TNF-TNFR system very complex. The dual TNF function for either cell death or survival upon interaction of members of the TNF ligand family with members of the TNF receptor family will be discussed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TUMOR-NECROSIS-FACTOR; NF-KAPPA-B; FACTOR-ALPHA; MOLECULAR-CLONING; LYMPHOTOXIN LT; CELL-DEATH; ACTIVATION; EXPRESSION; APOPTOSIS; LIGAND; LT alpha; LT beta receptor; p55TNFR; p75TNFR; TNF; TNF receptor |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Immunologie Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 11 Jun 2021 06:31 |
| Last Modified: | 11 Jun 2021 06:31 |
| URI: | https://pred.uni-regensburg.de/id/eprint/39803 |
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