Lenhart, Markus and Framme, Nicola and Voelk, Markus and Strotzer, Michael and Manke, Christoph and Nitz, Wolfgang G. and Finkenzeller, Thomas and Feuerbach, Stefan and Link, Johann (2002) Time-resolved contrast-enhanced magnetic resonance angiography of the carotid arteries - Diagnostic accuracy and inter-observer variability compared with selective catheter angiography. INVESTIGATIVE RADIOLOGY, 37 (10). pp. 535-541. ISSN 0020-9996
Full text not available from this repository. (Request a copy)Abstract
RATIONALE AND OBJECTIVES. To assess the diagnostic accuracy and interobserver variability of contrast-enhanced magnetic resonance angiography (CE-MRA) in a time-resolved technique. compared with digital subtraction angiography (x-ray DSA) in patients with suspected stenoses of the internal carotid artery. MATERIALS AND METHODS. A total of 43 patients. were enrolled in this prospective study. All patients underwent selective x-ray DSA involving a total of 84 carotid arteries. CE-MRA was performed in a time-resolved technique with a fast gradient-echo sequence on a 1.5 T MR scanner: TR 3.8 milliseconds, TE 1.49 milliseconds. Four consecutive measurements, each a duration of 10 seconds, were performed with omission of measuring bolus transit time. Four independent radiologists scored the degree of stenosis. The interobserver variability was calculated for CE-MRA and x-ray DSA. RESULTS. In the 43 cases, at least one MRA measurement showed arterial contrast without venous degradation. Compared with x-ray DSA the mean sensitivity and specificity for grading stenosis greater than or equal to 70% were 98% and 86%, respectively. The interobserver agreement was substantial with no significant difference between CE-MRA (kappa value 0.794) and x-ray DSA (K value 0.786). CONCLUSIONS. The short acquisition time of a fast CE-MRA sequence allows a selective visualization of the internal carotid arteries without degradation from venous enhancement. It is a reliable method with a good interobserver agreement.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 3D MR DSA; CONVENTIONAL ANGIOGRAPHY; STENOSIS; ENDARTERECTOMY; BIFURCATION; carotid arteries; MR, carotid arteries; stenosis or obstruction, Magnetic Resonance (MR); vascular studies |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Oct 2021 05:26 |
| Last Modified: | 05 Oct 2021 05:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/39830 |
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