Gege, Christian and Geyer, Armin and Schmidt, Richard R. (2002) Carbohydrate-carbohydrate recognition between Lewis X blood group antigens, mediated by calcium ions. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (15). pp. 2475-2485. ISSN 1434-193X, 1099-0690
Full text not available from this repository. (Request a copy)Abstract
Bivalent Lewis X (Le(x)) oligosaccharides were synthesised in order to study the conformational details of carbohydrate clusters by NMR spectroscopy. To this end, two Le(x) trisaccharide moieties (1) were covalently linked through the 6-hydroxy group or through the anomeric oxygen of GlcNAc to yield dimers 2 and 3, respectively. The two Le(x) halves of the model saccharide 2 exhibited cooperativity in calcium binding. Three different lactosides served as control compounds for NMR titration with calcium chloride.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LACTONEO-SERIES ANTIGENS; CELL-ADHESION; METHYLTHIOMETHYL ETHERS; BINDING; GLYCOSPHINGOLIPIDS; GLYCOSYLATION; GLYCOLIPIDS; PROTECTION; COMPLEX; LE(X); carbohydrates; Lewis X; glycosylation; NMR spectroscopy; polyvalency |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Sep 2021 06:04 |
| Last Modified: | 07 Sep 2021 06:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40024 |
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