Reinhold, Dirk and Kaehne, T. and Steinbrecher, Andreas and Wrenger, S. and Neubert, K. and Ansorge, S. and Brocke, S. (2002) The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity. BIOLOGICAL CHEMISTRY, 383 (7-8). pp. 1133-1138. ISSN 1431-6730
Full text not available from this repository.Abstract
Activated T lymphocytes express high levels of dipeptidyl peptidase IV (DP IV)/CD26. Recent studies support the notion that DP IV may play an important role in the regulation of differentiation and growth of T lymphocytes. This article gives a short overview on DP IV/CD26 expression and effects on immune cells in vitro and in vivo. A major focus of this review are clinical aspects of the function of CD26 on hematopoietic cells and the potential usage of synthetic DP IV inhibitors as therapeutics in inflammatory disorders.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSFORMING GROWTH-FACTOR-BETA-1 TGF-BETA-1; MESSENGER-RNA EXPRESSION; PWM-STIMULATED PBMC; IN-VIVO; CD26; LYMPHOCYTES; INHIBITORS; GROWTH; SUPPRESSION; SECRETION; autoimmune diseases; CD26; dipeptidyl peptidase IV; T cell activation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 09 Jun 2021 07:26 |
| Last Modified: | 09 Jun 2021 07:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40097 |
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