Grossmann, J. (2002) Molecular mechanisms of "detachment-induced apoptosis-Anoikis". APOPTOSIS, 7 (3). pp. 247-260. ISSN 1360-8185, 1573-675X
Full text not available from this repository.Abstract
Apoptosis following loss of cell anchorage is of relevance for development, tissue homeostasis and disease. In the following the role of cell-matrix anchorage as well as cell-cell anchorage for cell survival and apoptosis is reviewed and the complex molecular mechanisms inducing and perpetuating detachment-induced apoptosis will be discussed with special emphasis on the role of caspases, p53, bcl-2 family members and the Fas signaling pathway.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FOCAL ADHESION KINASE; INTEGRIN-LINKED KINASE; PROGRAMMED CELL-DEATH; INTESTINAL EPITHELIAL-CELLS; ANCHORAGE-INDEPENDENT GROWTH; ACTIVATED PROTEIN-KINASE; COLON-CARCINOMA CELLS; PHOSPHOINOSITIDE 3-OH KINASE; MEDIATED SURVIVAL SIGNALS; JUN NH2-TERMINAL KINASE; anoikis; apoptosis; cadherins; detachment-induced apoptosis; integrins |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Petra Gürster |
| Date Deposited: | 08 Jun 2021 10:05 |
| Last Modified: | 08 Jun 2021 10:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40170 |
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