Weber, Stefan and Hoeher, Martin and Schultes, Dominik (2016) First results and follow-up of a second-generation circular mapping and ablation catheter. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 47 (2). pp. 213-219. ISSN 1383-875X, 1572-8595
Full text not available from this repository. (Request a copy)Abstract
Pulmonary vein isolation with radiofrequency energy is widely used as a strategy for catheter ablation of atrial fibrillation (AF). Anatomically designed catheters have been developed to increase the efficiency of AF ablation procedures. The second-generation circular ablation catheter, PVAC GOLD, was re-designed to improve energy delivery and mitigate emboli. We investigated the procedural efficiency, biophysics, and chronic efficacy of PVAC GOLD in patients with AF. We consecutively enrolled 40 patients (60 +/- 11 years) with highly symptomatic, drug refractory AF. The first 20 patients were treated with the first-generation PVAC. The subsequent 20 patients were treated with the second-generation PVAC GOLD catheter. All patients were followed up at 3, 6, and 12 months. All 164 targeted PVs were successfully isolated. Ablations performed with PVAC GOLD showed a significant reduction in total number of ablations needed for PVI, fluoroscopy, and procedure times compared to PVAC (34.7 +/- 7.0 vs. 27.0 +/- 6.5; p = 0.009), fluoroscopy (29.5 +/- 9.5 vs. 23.4 +/- 7.0; p = 0.026), and procedure time (93.8 +/- 18.9 vs. 83.1 +/- 10.6; p = 0.033). PVAC GOLD showed improved biophysics including a reduction of low power ablations and an increase in mean effective energy delivery. At 12 months follow-up, AF recurrence rates were comparable in the two groups (35 vs. 30 %; p = 0.735). There were no adverse events. The redesigned PVAC GOLD catheter demonstrates a reduction in radiofrequency ablation and procedure time and improved biophysics while maintaining chronic efficacy compared to the first-generation PVAC.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PULMONARY VEIN ISOLATION; PAROXYSMAL ATRIAL-FIBRILLATION; DUTY-CYCLED BIPOLAR; UNIPOLAR RADIOFREQUENCY ENERGY; BY-POINT ABLATION; IRRIGATED RADIOFREQUENCY; MULTIELECTRODE ABLATION; TRIAL; MICROEMBOLISM; IMPACT; Atrial fibrillation; Catheter ablation; Phased RF; Multi-electrode ablation catheter |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Apr 2019 08:40 |
| Last Modified: | 24 Apr 2019 08:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/4031 |
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