Yacoub-George, Erwin and Meixner, Leonhard and Scheithauer, Waltraud and Koppi, Andreas and Drost, Stephan and Wolf, Hans and Danapel, Christine and Feller, Klaus A. (2002) Chemiluminescence multichannel immunosensor for biodetection. ANALYTICA CHIMICA ACTA, 457 (1): PII S0003-. pp. 3-12. ISSN 0003-2670
Full text not available from this repository. (Request a copy)Abstract
An improved portable detector for biological compounds, the chemiluminescence multichannel immunosensor (CL-MADAG), has been developed and characterised. The device is based on a capillary ELISA technique in combination with a miniaturised fluidics system and uses chemiluminescence as the detection principle. The fluidics system construction allows three chemiluminescence immunoassays to be performed simultaneously within three fused silica capillaries (FSC). The CL-MADAG was characterised in a seizes of experiments with staphylococcal enterotoxin B (SEB) as a model toxin, the bacterial phage virus M 13 as a virus simulant, and a pathogenic strain of Escherichia coli as simulant for bacteria. It was shown that the CL-MADAG can assay liquid samples for these substances within 24 min. The detection limits were 5 ng/ml for SEB, 10(5) efu/ml for E. coli O157:H7 and 10(7) pfu/ml for M13. (C) 2002 Elsevier Science B.V All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BIOLOGICAL WARFARE AGENTS; BIOSENSOR; IDENTIFICATION; SYSTEM; ASSAY; biosensor; chemiluminescence; immunoassay; multianalyte detection |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Nov 2021 07:47 |
| Last Modified: | 02 Nov 2021 07:47 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40380 |
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