Gum, F. and Scherer, J. and Bogner, Ludwig and Solleder, M. and Rhein, B. and Bock, M. (2002) Preliminary study on the use of an inhomogeneous anthropomorphic Fricke gel phantom and 3D magnetic resonance dosimetry for verification of IMRT treatment plans. PHYSICS IN MEDICINE AND BIOLOGY, 47 (7): PII S0031-. N67-N77. ISSN 0031-9155
Full text not available from this repository. (Request a copy)Abstract
An inhomogeneous anthropomorphic phantom of the human thorax including lungs and spine was developed for verification of three-dimensional (3D) intensity-modulated radiotherapy (IMRT). The phantom and spinal cord were filled with undiluted Fricke gel, whereas the lungs were filled with a special low-density Fricke gel. Based on a computed tomography scan of the phantom. an intensity-modulated stereotactic radiotherapy plan for a bronchial carcinoma was calculated using an inverse planning system (KonRad, DKFZ Heidelberg, Germany). The plan consisted of seven beams delivered in a step and shoot technique out of 67 sub-fields. Immediately after irradiation 3D magnetic resonance (MR) imaging of the phantom was performed using a special pulse sequence for T, relaxometry. From the MR image data maps of the longitudinal relaxation rate R-1 = 1 / T-1 were calculated. The R-1 maps were converted to dose-proportional image data and compared to planning data. Measurement and planning show good agreement in regions of standard Fricke gel with an average deviation below 5%. In regions of the low-density Fricke gel, deviations; are higher due to a decreased signal-to-noise ratio in the MR measurement. In these areas also a different sensitivity of the dose response was observed as compared to standard Fricke gel. The inhomogeneous thorax phantom has proven to be a useful pre-clinical tool for 3D methodical verifications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POLYMER GEL; DOSE DISTRIBUTIONS; RADIATION; MRI; RADIOTHERAPY; ACCURACY; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Strahlentherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Nov 2021 09:16 |
| Last Modified: | 02 Nov 2021 09:16 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40388 |
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