May, Arne and Gamulescu, M. A. and Bogdahn, Ulrich and Lohmann, C. P. (2002) Intractable eye pain: indication for triptans. CEPHALALGIA, 22 (3). pp. 195-196. ISSN 0333-1024
Full text not available from this repository. (Request a copy)Abstract
Management of pain is difficult in many eye diseases. Particularly in patients undergoing surgical procedures, postoperative intractable pain is a major concern and severely influences the patient's comfort. We present 13 patients (eight male, five female, mean age 36 years) in whom sumatriptan, a highly selective 5-HT1B/1D agonist that is normally used as a specific anti-migraine drug, was used for the treatment of pain following photorefractive keratectomy (PRK). In two patients both eyes were operated on different days, resulting in a total of 15 operated eyes. A positive clinical response was achieved in all patients. In particular, in four patients, who received a second dose prophylactically 4 h following the first dose and before the recurrence of pain, we achieved excellent efficacy and stable control of pain. Further controlled studies are needed to investigate the usefulness of 5-HT1B/1D agonists in painful eye conditions.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PHOTOREFRACTIVE KERATECTOMY; SUMATRIPTAN; eye pain; photorefractive keratectomy; sumatriptan |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Augenheilkunde Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Nov 2021 10:40 |
| Last Modified: | 02 Nov 2021 10:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40401 |
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